DNA-(apurinic or apyrimidinic site) endonuclease activity

Term ID

GO:0003906

Synonyms

• AP endonuclease class I activity
• AP site-DNA 5'-phosphomonoester-lyase activity
• apurinic/apyrimidinic endodeoxyribonuclease activity
• deoxyribonuclease (apurinic or apyrimidinic) activity
• DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity
• endonuclease VIII activity
• UV endonuclease

Definition

Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). AP_endonuclease

References

• Reactome:R-HSA-110375
• Reactome:R-HSA-5649711
• Reactome:R-HSA-5649725

Ontology

GO: Molecular Function    QuickGO    AmiGO