Search Ontology:
GO: Molecular Function

alkylbase DNA N-glycosylase activity

Term ID
GO:0003905
Synonyms
  • 3-methyladenine DNA glycosylase II
  • AlkA
  • alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
  • alkylbase DNA glycosidase activity
  • deoxyribonucleate 3-methyladenine glycosidase II
  • DNA glycosidase II activity
  • DNA-3-methyladenine glycosidase II activity
  • DNA-3-methyladenine glycosylase II
Definition
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. (3)
References
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
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has subtype
Phenotype
Phenotype caused by Genes
Citations
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