6-pyruvoyltetrahydropterin synthase activity

Term ID

GO:0003874

Synonyms

• 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity
• 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)
• 6-pyruvoyl tetrahydrobiopterin synthase activity
• PTPS activity

Definition

Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H+ + triphosphate. 4.2.3.12

References

• EC:4.2.3.12
• KEGG_REACTION:R04286
• MetaCyc:4.2.3.12-RXN
• RHEA:22048
• Reactome:R-HSA-1474184

Ontology

GO: Molecular Function    QuickGO    AmiGO