germinal center B cell differentiation

Term ID

GO:0002314

Synonyms

• germinal center B cell development
• germinal center B lymphocyte differentiation
• germinal center B-cell differentiation
• germinal center B-lymphocyte differentiation

Definition

The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). 0781735149

References

Ontology

GO: Biological Process    QuickGO    AmiGO