epithelial to mesenchymal transition

Term ID

GO:0001837

Synonyms

EMT
epithelial-mesenchymal transition
mesenchymal cell differentiation from epithelial cell

Definition

A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. 14701881

References

Reactome:R-HSA-9758919

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: mesenchymal cell differentiation

mesenchymal cell differentiation Show first 5 Terms
has subtype: cardiac epithelial to mesenchymal transition clearance of cells from fusion plate by epithelial to mesenchymal transition epicardial cell to mesenchymal cell transition mesodermal to mesenchymal transition involved in gastrulation neural crest formation

cardiac epithelial to mesenchymal transition clearance of cells from fusion plate by epithelial to mesenchymal transition epicardial cell to mesenchymal cell transition mesodermal to mesenchymal transition involved in gastrulation neural crest formation Show first 5 Terms
negatively regulated by: negative regulation of epithelial to mesenchymal transition

negative regulation of epithelial to mesenchymal transition Show first 5 Terms
positively regulated by: positive regulation of epithelial to mesenchymal transition

positive regulation of epithelial to mesenchymal transition Show first 5 Terms
regulated by: regulation of epithelial to mesenchymal transition

regulation of epithelial to mesenchymal transition Show first 5 Terms

Phenotype

Phenotype caused by Genes