fatty acid alpha-oxidation

Term ID

GO:0001561

Synonyms

Definition

A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway. 10198260

References

• MetaCyc:PWY-2501
• Reactome:R-HSA-389599

Ontology

GO: Biological Process    QuickGO    AmiGO