mRNA splicing, via spliceosome

Term ID

GO:0000398

Synonyms

mRNA splicing
nuclear mRNA splicing via U12-type spliceosome
nuclear mRNA splicing via U2-type spliceosome
nuclear mRNA splicing, via spliceosome
pre-mRNA splicing
splicing AT-AC intron
splicing GT-AG intron

Definition

The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. (2)

References

Reactome:R-HSA-72163
Reactome:R-HSA-72165

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: spliceosomal complex assembly spliceosomal complex disassembly spliceosomal conformational changes to generate catalytic conformation spliceosomal snRNP assembly

spliceosomal complex assembly spliceosomal complex disassembly spliceosomal conformational changes to generate catalytic conformation spliceosomal snRNP assembly Show first 5 Terms
is a type of: mRNA processing RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

mRNA processing RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Show first 5 Terms
has subtype: alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome mRNA trans splicing, via spliceosome spliceosome-depend formation of circular RNA

alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome mRNA trans splicing, via spliceosome spliceosome-depend formation of circular RNA Show first 5 Terms
negatively regulated by: negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA splicing, via spliceosome Show first 5 Terms
positively regulated by: positive regulation of mRNA splicing, via spliceosome

positive regulation of mRNA splicing, via spliceosome Show first 5 Terms
regulated by: regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome Show first 5 Terms

Phenotype

Phenotype caused by Genes