tRNA 2'-phosphotransferase activity

Term ID

GO:0000215

Synonyms

• 2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity
• 2'-phospho-tRNA:NAD+ phosphotransferase activity
• 2'-phosphotransferase activity
• Tpt1
• Tpt1p
• yeast 2'-phosphotransferase activity

Definition

Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate. (2)

References

• EC:2.7.1.160
• MetaCyc:2.7.1.160-RXN
• RHEA:23324

Ontology

GO: Molecular Function    QuickGO    AmiGO