Search Ontology:
Evidence Ontology
position-specific scoring matrix motif search evidence
- Term ID
- ECO:0005536
- Synonyms
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- PSSM
- PSSM motif search
- Definition
- A type of motif similarity evidence where the motif is represented by a position-specific frequency matrix (PSFM) that specifies the frequency of each base at each position of the motif, from which a position-specific scoring matrix (PSSM) can be derived under the framework of a log-likelihood ratio providing a scoring system based on the likelihood of a sequence given the motif, versus a genomic-frequency based null hypothesis. 10812473
- References
- Ontology
- Evidence Ontology