ultraviolet light footprinting evidence

Term ID

ECO:0001826

Synonyms

• ultraviolet footprinting
• UV footprinting

Definition

A type of nucleic acid binding evidence where DNA is non-specifically fragmented with ultraviolet light while protein-bound regions are protected from UV damage and strand breakage patterns are analyzed by PAGE and sequenced to detect protein-DNA contacts. (2)

References

Ontology

Evidence Ontology