Werner syndrome

Term ID

DOID:5688

Synonyms

• adult premature ageing syndrome
• adult progeria
• Werner's syndrome
• WS

Definition

A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8. (3)

References

• GARD:7885
• MESH:D014898
• MIM:277700
• NCI:C3447
• ORDO:902
• SNOMEDCT_US_2023_03_01:51626007
• UMLS_CUI:C0043119

Ontology

Human Disease   ( DOID:5688 )