Search Ontology:
Human Disease

Lynch syndrome

Term ID
DOID:3883
Synonyms
  • Hereditary Defective Mismatch Repair syndrome
  • Hereditary non-polyposis colon cancer
  • Hereditary non-polyposis colon cancer syndrome
  • Hereditary non-polyposis colorectal cancer
  • Hereditary non-polyposis colorectal cancer syndrome
  • Hereditary nonpolyposis colon cancer
  • Hereditary nonpolyposis colon cancer syndrome
  • hereditary nonpolyposis colorectal cancer
  • Hereditary nonpolyposis colorectal cancer syndrome
  • hereditary nonpolyposis colorectal neoplasm
  • HNPCC
Definition
A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers. (2)
References