Search Ontology:
Human Disease

acute myeloid leukemia with t(8;21); (q22; q22.1)

Term ID
DOID:0081093
Synonyms
  • Acute Myeloid Leukemia with t(8;21); (q22; q22.1); RUNX1-RUNX1T1
  • acute myeloid leukemia, t(8;21)(q22;q22)
Definition
An acute myeloid leukemia associated with t(8;21)(q22;q22) resulting in RUNX1-RUNX1T1 fusion protein expression. The bone marrow and the peripheral blood show large myeloblasts with abundant basophilic cytoplasm, often containing azurophilic granules. (2)
References
  • ICDO:9896/3
  • NCI:C9288
Ontology
Human Disease   ( DOID:0081093 )
Relationships
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Genes Involved
Zebrafish Models