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Human Disease

maple syrup urine disease type IB

Term ID
DOID:0061206
Synonyms
Definition
A maple syrup urine disease that is characterized by mental and physical retardation, feeding problems, and a maple syrup odor to the urine and that has_material_basis_in homozygous or compound heterozygous mutation in the BCKDHB gene, which encodes a subunit of the branched-chain alpha-keto acid dehydrogenase complex (BCKDC), on chromosome 6q14. https://pubmed.ncbi.nlm.nih.gov/7883996/
References
Ontology
Human Disease   ( DOID:0061206 )
Relationships
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Genes Involved
Zebrafish Models