immunodeficiency 119

Term ID

DOID:0061085

Synonyms

Definition

A T cell, B cell, and NK cell deficiency that is characterized by the onset of recurrent upper and lower respiratory infections and warts in childhood and that has_material_basis_in homozygous mutation in the ICOSLG gene on chromosome 21q22. Affected individuals are susceptible to chronic DNA-based viral infections, including HPV and HSV. https://pubmed.ncbi.nlm.nih.gov/30498080/

References

• MIM:620825

Ontology

Human Disease   ( DOID:0061085 )