Grn-related frontotemporal lobar degeneration with Tdp43 inclusions

Term ID

DOID:0060672

Synonyms

Definition

A frontotemporal dementia characterized by variable phenotypic expression typically including social, behavioral, or language deterioration, rather than memory or motor deficits and the presence of TARDBP-positive inclusions that has_material_basis_in mutation in the GRN gene on chromosome 17q21.31. (2)

References

• ICD10CM:G31.0
• OMIM:607485

Ontology

Human Disease   ( DOID:0060672 )