basophil progenitor cell

Term ID

CL:0000613

Synonyms

BaP
basophilic stem cell
CFU-Bas
colony forming unit basophil

Definition

A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. http://www.copewithcytokines.de

References

Ontology

Cell Ontology

Relationships

develops from: basophil mast progenitor cell

basophil mast progenitor cell Show first 5 Terms
develops into: basophilic myeloblast

basophilic myeloblast Show first 5 Terms
is a type of: granulocytopoietic cell myeloid cell

granulocytopoietic cell myeloid cell Show first 5 Terms
has subtype: Fc-epsilon RIalpha-high basophil progenitor cell

Fc-epsilon RIalpha-high basophil progenitor cell Show first 5 Terms
capable_of: basophil differentiation

basophil differentiation Show first 5 Terms
has_high_plasma_membrane_amount: high affinity immunoglobulin epsilon receptor subunit alpha

high affinity immunoglobulin epsilon receptor subunit alpha Show first 5 Terms
has_low_plasma_membrane_amount: transmembrane emp24 domain-containing protein 1

transmembrane emp24 domain-containing protein 1 Show first 5 Terms
has_part: CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor

CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor Show first 5 Terms
lacks_plasma_membrane_part: CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule ... Show All 13 Terms

CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule integrin alpha-M lymphocyte antigen 6G lymphocyte antigen 76 mast/stem cell growth factor receptor membrane-spanning 4-domains subfamily A member 1 neural cell adhesion molecule 1 T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD8 alpha chain Show first 5 Terms