alveolar macrophage

Term ID

CL:0000583

Synonyms

dust cell
MF.Lu

Definition

A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. A11.329.372.600

References

BTO:0000802
CALOHA:TS-0030
FMA:83023

Ontology

Cell Ontology

Relationships

is a type of: tissue-resident macrophage

tissue-resident macrophage Show first 5 Terms
capable_of: antigen processing and presentation

antigen processing and presentation Show first 5 Terms
has_low_plasma_membrane_amount: integrin alpha-M

integrin alpha-M Show first 5 Terms
has_plasma_membrane_part: C-type lectin domain family 7 member A EGF-like module-containing mucin-like hormone receptor-like 1 integrin alpha-X macrophage mannose receptor 1 macrosialin ... Show All 6 Terms

C-type lectin domain family 7 member A EGF-like module-containing mucin-like hormone receptor-like 1 integrin alpha-X macrophage mannose receptor 1 macrosialin sialoadhesin Show first 5 Terms
lacks_plasma_membrane_part: CX3C chemokine receptor 1

CX3C chemokine receptor 1 Show first 5 Terms
located_in: alveolus of lung

alveolus of lung Show first 5 Terms