Search Ontology:
ChEBI
trichlormethiazide
- Term ID
- CHEBI:9683
- Synonyms
-
- 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- hydrotrichlorothiazide
- trichlormethiazide
- trichlormethiazidum
- triclormetiazida
- Definition
- A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.
- References
-
- cas:133-67-5
- drugbank:DB01021
- drugcentral:2733
- kegg.compound:C07767
- kegg.drug:D00658
- lincs.smallmolecule:LSM-4383
- pubmed:21605415
- pubmed:24678944
- pubmed:25692026
- pubmed:25938807
- pubmed:28089902
- pubmed:28166217
- pubmed:29438107
- wikipedia.en:Trichlormethiazide
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from trichlormethiazide
Phenotype where environments contain trichlormethiazide
Phenotype modified by environments containing trichlormethiazide
Phenotype affecting trichlormethiazide
Human Disease Model