torasemide

Term ID

CHEBI:9637

Synonyms

• 1-isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
• 4-(3-methylanilino)-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide
• AC 4464
• AC-4464
• AC4464
• BM 02015
• BM-02.015
• BM-02015
• BM02.015
• BM02015
• Demadex
• JDL 464
• JDL-464
• Luprac
• N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
• N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
• N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
• torasemida
• torasemide
• torasemidum
• Torem
• Torsemide
• Unat

Definition

An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure.

References

• cas:56211-40-6
• drugbank:DB00214
• drugcentral:2708
• hmdb:HMDB0014359
• kegg.drug:D00382
• lincs.smallmolecule:LSM-2662
• pubmed:21391491
• pubmed:21906812
• pubmed:22030290
• pubmed:22364690
• pubmed:22407343
• pubmed:23013124
• pubmed:23237447
• pubmed:23792294
• pubmed:23837587
• pubmed:23877845
• pubmed:24040049
• pubmed:24243991
• pubmed:24367917
• pubmed:24432564
• pubmed:24554915
• pubmed:28891228
• pubmed:29488197
• pubmed:30649675
• pubmed:30827731
• pubmed:31124957
• pubmed:31436024
• pubmed:31699358
• pubmed:31809955
• pubmed:32098657
• pubmed:32302808
• pubmed:32411731
• reaxys:498515
• wikipedia.en:Torasemide

Ontology

ChEBI  ( EBI )

Resources

CTD