(S)-timolol (anhydrous)

Term ID

CHEBI:9599

Synonyms

(-)-3-morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-(1,1-(dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-tert-Butylamino-3-(4-morpholin-4-yl-[1,2,5]thiadiazol-3-yloxy)-propan-2-ol
(S)-timolol
1-(tert-butylamino)-3-[4-(1,4-oxazinan-4-yl)-1,2,5-thiadiazol-3-yloxy]-(2S)-propan-2-ol
S-(-)-3-(3-tert-butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
Timolol

Definition

The (S)-(−) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.

References

cas:26839-75-8
drugbank:DB00373
drugcentral:4061
kegg.compound:C07141
kegg.drug:D08600
lincs.smallmolecule:LSM-2176
patent:DE1925956
patent:DE2915955
patent:US3655663
patent:US3657237
pdb-ccd:TIM
pubmed:10891117
pubmed:11300874
pubmed:11728183
pubmed:11784135
pubmed:14971904
pubmed:15027870
pubmed:15857133
pubmed:1635066
pubmed:2002467
pubmed:2579237
pubmed:2872332
pubmed:2892933
pubmed:2903243
pubmed:6094812
pubmed:6109024
pubmed:6113285
pubmed:6126588
pubmed:6134834
pubmed:8568799
pubmed:9288160
reaxys:1084707
wikipedia.en:Timolol

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from (S)-timolol (anhydrous)

Phenotype where environments contain (S)-timolol (anhydrous)

Phenotype modified by environments containing (S)-timolol (anhydrous)

Phenotype affecting (S)-timolol (anhydrous)

Human Disease Model