(S)-timolol (anhydrous)

Term ID

CHEBI:9599

Synonyms

• (-)-3-morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
• (2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
• (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
• (S)-1-(1,1-(dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
• (S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
• (S)-1-tert-Butylamino-3-(4-morpholin-4-yl-[1,2,5]thiadiazol-3-yloxy)-propan-2-ol
• (S)-timolol
• 1-(tert-butylamino)-3-[4-(1,4-oxazinan-4-yl)-1,2,5-thiadiazol-3-yloxy]-(2S)-propan-2-ol
• S-(-)-3-(3-tert-butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
• Timolol

Definition

The (S)-(-) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.

References

• Beilstein:1084707
• CAS:26839-75-8
• DrugBank:DB00373
• Drug_Central:4061
• KEGG:C07141
• KEGG:D08600
• LINCS:LSM-2176
• PDBeChem:TIM
• PMID:10891117
• PMID:11300874
• PMID:11728183
• PMID:11784135
• PMID:14971904
• PMID:15027870
• PMID:15857133
• PMID:1635066
• PMID:2002467
• PMID:2579237
• PMID:2872332
• PMID:2892933
• PMID:2903243
• PMID:6094812
• PMID:6109024
• PMID:6113285
• PMID:6126588
• PMID:6134834
• PMID:8568799
• PMID:9288160
• Patent:DE1925956
• Patent:DE2915955
• Patent:US3655663
• Patent:US3657237
• Reaxys:1084707
• Wikipedia:Timolol

Ontology

ChEBI  ( EBI )

Resources

CTD