tioguanine

Term ID

CHEBI:9555

Synonyms

• 2-Amino 6MP
• 2-Amino-1,7-dihydro-6H-purine-6-thione
• 2-amino-1,9-dihydro-6H-purine-6-thione
• 2-amino-1,9-dihydropurine-6-thione
• 2-Amino-6-mercaptopurine
• 2-Amino-6-merkaptopurin
• 2-Amino-6-purinethiol
• 2-Aminopurin-6-thiol
• 2-Aminopurine-6(1H)-thione
• 2-Aminopurine-6-thiol
• 6-Mercapto-2-aminopurine
• 6-Mercaptoguanine
• 6-TG
• 6-thioguanine
• TG
• ThG
• Thioguanine
• Tioguanin
• tioguanina
• tioguanine
• tioguaninum

Definition

A 2-aminopurine that is the 6-thiono derivative of 2-amino-1,9-dihydro-6H-purine. Incorporates into DNA and inhibits synthesis. Used in the treatment of leukaemia.

References

• CAS:154-42-7
• DrugBank:DB00352
• Drug_Central:2632
• KEGG:C07648
• KEGG:D08603
• KNApSAcK:C00018807
• LINCS:LSM-6723
• MetaCyc:CPD-5721
• PDBeChem:DX4
• PMID:21803983
• PMID:22178190
• PMID:22245861
• PMID:22261533
• PMID:22280519
• PMID:22563779
• PMID:22646133
• PMID:22822082
• PMID:22983983
• PMID:23259153
• PMID:23261807
• PMID:23377192
• PMID:23377281
• PMID:23393198
• PMID:25542975
• PMID:28166217
• Reaxys:1074099
• Wikipedia:Thioguanine

Ontology

ChEBI  ( EBI )

Resources

CTD