thiamine(1+) diphosphate

Term ID

CHEBI:9532

Synonyms

3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)thiazolium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-[2-(diphosphooxy)ethyl]-4-methyl-1,3-thiazol-3-ium
ThDP
thiamin diphosphate
thiamine-pyrophosphate
ThPP
TPP

Definition

A thiamine phosphate that is thiamine(1+) in which the hydroxy group has been replaced by a diphosphate group. It is the active form of vitamin B1 and an essential cofactor for enzymes in key metabolic pathways.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: thiamine phosphate vitamin B1

thiamine phosphate vitamin B1 Show first 5 Terms
has_role: cofactor fundamental metabolite

cofactor fundamental metabolite Show first 5 Terms
inverse has_part: thiamine(1+) diphosphate chloride

thiamine(1+) diphosphate chloride Show first 5 Terms
inverse is_conjugate_base_of: thiamine(1+) diphosphate(1-)

thiamine(1+) diphosphate(1-) Show first 5 Terms
is_conjugate_acid_of: thiamine(1+) diphosphate(1-)

thiamine(1+) diphosphate(1-) Show first 5 Terms

Phenotype

Phenotype resulting from thiamine(1+) diphosphate

Phenotype where environments contain thiamine(1+) diphosphate

Phenotype modified by environments containing thiamine(1+) diphosphate

Human Disease Model