Search Ontology:
ChEBI

molibresib

Term ID
CHEBI:95082
Synonyms
  • 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
  • GSK 525762A
  • GSK-525762A
  • GSK525762
  • GSK525762A
  • I-BET 762
  • I-BET-762
  • I-BET762
  • molibresib
  • molibresibum
Definition
A member of the class of triazolobenzodiazepine that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine substituted by methyl, 2-(ethylamino)-2-oxoethyl, 4-chlorophenyl, and methoxy groups at positions 1, 4S, 6, and 8, respectively. It is an orally bioavailable inhibitor of BET family of proteins that has demonstrated antitumour activity in preclinical models of solid and hematologic malignancies.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from molibresib
Phenotype where environments contain molibresib
Phenotype modified by environments containing molibresib
Human Disease Model
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