methylstat

Term ID

CHEBI:95078

Synonyms

• (2E)-4-[hydroxy[4-[[[4-[[[(1-naphthalenylamino)carbonyl]oxy]methyl]phenyl]methyl]amino]butyl]amino]-4-oxo-2-butenoic acid methyl ester
• methyl (2E)-4-(hydroxy{4-[(4-{[(naphthalen-1-ylcarbamoyl)oxy]methyl}benzyl)amino]butyl}amino)-4-oxobut-2-enoate

Definition

A member of the class of naphthalenes that is naphthalene substituted by a {[(4-{[(4-{hydroxy[(2E)-4-methoxy-4-oxobut-2-enoyl]amino}butyl)amino]methyl}benzyl)oxy]carbonyl}amino group at position 1. It is an inhibitor of the Jumonji C domain-containing histone trimethyl demethylases.

References

• cas:1310877-95-2
• lincs.smallmolecule:LSM-43292
• pubmed:21585201
• pubmed:23725560
• pubmed:25733903
• pubmed:30589237
• pubmed:31320500
• pubmed:31509985
• pubmed:31833715
• pubmed:32111493
• pubmed:35838529
• pubmed:35985520
• pubmed:36402192
• pubmed:38421193

Ontology

ChEBI  ( EBI )