ricolinostat

Term ID

CHEBI:95073

Synonyms

2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]pyrimidine-5-carboxamide
ACY 1215
ACY-1215
ACY-63
ACY1215
N-[7-(hydroxyamino)-7-oxoheptyl]-2-(N-phenylanilino)-5-pyrimidinecarboxamide
ricolinostat
ricolinostatum

Definition

A member of the class of pyrimidines that is pyrimidine substituted by diphenylamino and [7-(hydroxyamino)-7-oxoheptyl]aminocarbonyl groups at positions 2 and 5, respectively. It is a histone deacetylase 6 inhibitor with potential antineoplastic activity.

References

cas:1316214-52-4
drugbank:DB12376
hmdb:HMDB0244543
kegg.drug:D10661
lincs.smallmolecule:LSM-6324
pdb-ccd:AH4
pubmed:22262760
pubmed:24844691
pubmed:25709080
pubmed:26116270
pubmed:28035401
pubmed:28747357
pubmed:29112935
pubmed:29203661
pubmed:29749542
pubmed:30028995
pubmed:30043566
pubmed:30050135
pubmed:30551507
pubmed:31244662
pubmed:31548177
pubmed:31571096
pubmed:32705192
pubmed:33458921
pubmed:34969757
pubmed:34998817
pubmed:35231828
pubmed:35652048
pubmed:35674911
pubmed:36578217
pubmed:36585452
pubmed:36588693
pubmed:37322365
pubmed:37322366
pubmed:37982151
pubmed:38231305
pubmed:38527593

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from ricolinostat

Phenotype where environments contain ricolinostat

Phenotype modified by environments containing ricolinostat

Phenotype affecting ricolinostat

Human Disease Model