Search Ontology:
ChEBI
pracinostat
- Term ID
- CHEBI:95071
- Synonyms
-
- (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide
- pracinostat
- pracinostatum
- SB 939
- SB-939
- SB939
- Definition
- A hydroxamic acid that is N-hydroxyacrylamide which is substituted at position 3 by a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). An orally available pan-histone deacetylase inhibitor with demonstrated activity in the treatment of advanced solid tumours.
- References
-
- cas:929016-96-6
- drugbank:DB05223
- lincs.smallmolecule:LSM-43290
- pubmed:21873472
- pubmed:22475363
- pubmed:22508312
- pubmed:23556431
- pubmed:23893953
- pubmed:25632070
- pubmed:25983041
- pubmed:26853619
- pubmed:27196751
- pubmed:27855304
- pubmed:28094841
- pubmed:28301600
- pubmed:28841236
- pubmed:30181244
- pubmed:30632841
- pubmed:30760466
- pubmed:30841499
- pubmed:30932330
- pubmed:31468521
- pubmed:31526347
- pubmed:31527052
- wikipedia.en:Pracinostat
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from pracinostat
Phenotype where environments contain pracinostat
Phenotype modified by environments containing pracinostat
Phenotype affecting pracinostat
Human Disease Model