tetrodotoxin

Term ID

CHEBI:9506

Synonyms

(1R,5R,6R,7R,9S,11R,12R,13S,14S)-14-(hydroxymethyl)-3-imino-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1(7,11).0(1,6)]tetradecane-5,9,12,13,14-pentol
Babylonia japonica toxin 1
BJT 1
fugu poison
maculotoxin
octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol
spheroidine
tarichatoxin
tetrodontoxin
Tetrodotoxin
tetrodotoxine
TTX

Definition

A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.

References

agr:IND607175662
beilstein:4156319
cas:4368-28-9
drugbank:DB05232
hmdb:HMDB0258938
kegg.compound:C11692
knapsack:C00055525
metacyc.compound:CPD-19561
pubmed:11024497
pubmed:22163187
pubmed:22412801
pubmed:22798951
pubmed:23261990
pubmed:23661608
pubmed:23866757
pubmed:23980434
pubmed:24121556
pubmed:24295175
pubmed:24566728
pubmed:28648727
pubmed:28817087
pubmed:31029635
pubmed:31833474
pubmed:31985136
pubmed:32210160
pubmed:32415408
pubmed:32625458
pubmed:32849450
pubmed:33276679
pubmed:33450969
pubmed:33540777
pubmed:33651884
pubmed:33805908
pubmed:33807311
pubmed:33830775
pubmed:33913398
pubmed:33955768
pubmed:34067828
pubmed:34207879
pubmed:34209313
pubmed:34273772
pubmed:34357955
pubmed:34357968
pubmed:34437388
pubmed:34454925
pubmed:9559733
reaxys:6072946
wikipedia.en:Tetrodotoxin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from tetrodotoxin

Phenotype where environments contain tetrodotoxin

Phenotype modified by environments containing tetrodotoxin

Phenotype affecting tetrodotoxin

Human Disease Model