tetrodotoxin

Term ID

CHEBI:9506

Synonyms

(1R,5R,6R,7R,9S,11R,12R,13S,14S)-14-(hydroxymethyl)-3-imino-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1(7,11).0(1,6)]tetradecane-5,9,12,13,14-pentol
Babylonia japonica toxin 1
BJT 1
fugu poison
maculotoxin
octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol
spheroidine
tarichatoxin
tetrodontoxin
Tetrodotoxin
tetrodotoxine
TTX

Definition

A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: azatetracycloalkane oxatetracycloalkane quinazoline alkaloid

azatetracycloalkane oxatetracycloalkane quinazoline alkaloid Show first 5 Terms
has_role: animal metabolite bacterial metabolite marine metabolite neurotoxin voltage-gated sodium channel blocker

animal metabolite bacterial metabolite marine metabolite neurotoxin voltage-gated sodium channel blocker Show first 5 Terms
inverse has_functional_parent: (+/-)-tetrodotoxin (11S,13S)-3-Amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-9-olate (11s,13s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol Anhydrotetrodotoxin

(+/-)-tetrodotoxin (11S,13S)-3-Amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-9-olate (11s,13s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol Anhydrotetrodotoxin Show first 5 Terms
inverse is_conjugate_acid_of: tetrodotoxin(1+)

tetrodotoxin(1+) Show first 5 Terms
is_conjugate_base_of: tetrodotoxin(1+)

tetrodotoxin(1+) Show first 5 Terms

Phenotype

Phenotype resulting from tetrodotoxin

Phenotype where environments contain tetrodotoxin

Phenotype modified by environments containing tetrodotoxin

Human Disease / Model Data

Citations