MST-312

Term ID

CHEBI:95003

Synonyms

MST 312
MST312
N,N'-(1,3-phenylene)bis(2,3-dihydroxybenzamide)
N,N'-benzene-1,3-diylbis(2,3-dihydroxybenzamide)
N,N'-bis(2,3-dihydroxybenzoyl)-1,3-phenylenediamine
N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide
telomerase inhibitor IX

Definition

A member of the class of benzamides that results from the formal condensation of the two amino groups of benzene-1,3-diamine with the carboxylic acid groups of two molar equivalents of 2,3-dihydroxybenzoic acid. It is telomerase inhibitor (IC₅₀ = 0.67 μM in a TRAP assay) and exhibits antineoplastic activity.

References

cas:368449-04-1
lincs.smallmolecule:LSM-6230
pubmed:12479362
pubmed:25596016
pubmed:26022158
pubmed:26022559
pubmed:26178994
pubmed:27279256
pubmed:28520570
pubmed:29604359
pubmed:30170357
pubmed:31012504
pubmed:31029779
pubmed:31921617
pubmed:33922244
pubmed:34957975
pubmed:35809296
pubmed:35811464
pubmed:36274541
pubmed:36378860
pubmed:38216120
pubmed:38252348
pubmed:38765717

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from MST-312

Phenotype where environments contain MST-312

Phenotype modified by environments containing MST-312

Phenotype affecting MST-312

Human Disease Model