pirarubicin

Term ID

CHEBI:94770

Synonyms

• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
• (2''R)-4'-O-tetrahydropyranyladriamycin
• (2''R)-4'-O-tetrahydropyranyldoxorubicin
• (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
• 4'-O-tetrahydropyranyladriamycin
• adriamycin, tetrahydropyranyl
• pirarubicin
• pirarubicina
• pirarubicine
• pirarubicinum
• theprubicin
• therarubicin
• THP-ADM
• THP-adriamycin
• THP-doxorubicin

Definition

An anthracycline that is doxorubicin in which the hydroxy group at position 4' is replaced by a (2R)-tetrahydro-2H-pyran-2-yloxy group.

References

• cas:72496-41-4
• drugbank:DB11616
• drugcentral:2198
• kegg.drug:D01885
• lincs.smallmolecule:LSM-5899
• pubmed:3046496
• pubmed:37160625
• pubmed:37173953
• pubmed:37598394
• pubmed:37946994
• pubmed:38171901
• pubmed:38360289
• pubmed:38361605
• pubmed:38516760
• pubmed:38562460
• pubmed:38608986
• pubmed:38706852
• pubmed:38750718
• pubmed:39227014
• pubmed:39241516
• pubmed:39242397
• pubmed:39346118
• pubmed:39420738
• pubmed:39678572
• pubmed:39710273
• pubmed:40022852
• pubmed:40078190
• pubmed:40080123
• pubmed:40103905
• pubmed:40205399
• pubmed:40396269
• pubmed:40449451
• wikipedia.en:Pirarubicin

Ontology

ChEBI  ( EBI )