Search Ontology:
ChEBI

N-hydroxy-7-(naphthalen-2-ylthio)heptanamide

Term ID
CHEBI:94741
Synonyms
  • histone deacetylase inhibitor VI
  • HNHA
  • N-hydroxy-7-(2-naphthalenylthio)-heptanamide
  • N-hydroxy-7-(2-naphthalenylthio)heptanamide
  • N-hydroxy-7-(2-naphthylthio)heptanamide
  • N-hydroxy-7-(2-naphthylthio)heptanomide
  • N-hydroxy-7-(naphthalen-2-ylsulfanyl)heptanamide
  • N-hydroxy-7-naphthalen-2-ylsulfanylheptanamide
Definition
A member of the class of naphthalenes that is naphthalene substituted by a [7-(hydroxyamino)-7-oxoheptyl]sulfanediyl group at position 2. It is a histone deacetylase inhibitor that exhibits antineoplastic activity.
References
  • cas:926908-04-5
  • lincs.smallmolecule:LSM-5837
  • pubmed:17353008
  • pubmed:19718802
  • pubmed:21159061
  • pubmed:23953690
  • pubmed:24467283
  • pubmed:25613585
  • pubmed:26698299
  • pubmed:28142087
  • pubmed:29331886
  • pubmed:33430361
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from N-hydroxy-7-(naphthalen-2-ylthio)heptanamide
Phenotype where environments contain N-hydroxy-7-(naphthalen-2-ylthio)heptanamide
Phenotype modified by environments containing N-hydroxy-7-(naphthalen-2-ylthio)heptanamide
Phenotype affecting N-hydroxy-7-(naphthalen-2-ylthio)heptanamide
Human Disease Model