Search Ontology:
ChEBI

YK-4-279

Term ID
CHEBI:94301
Synonyms
  • 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
  • 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one
  • 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one
  • YK 4-279
  • YK 4279
  • YK4279
(all 6)
Definition
A member of the class of indolones that is 1,3-dihydro-2H-indol-2-one substituted by hydroxy, 2-(4-methoxyphenyl)-2-oxoethyl, chloro, and chloro groups at positions 3, 3, 4, and 7, respectively. It blocks RNA helicase A binding to EWS-FLI1, induces apoptosis, and exhibits antineoplastic activity.
References
(all 23)
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from YK-4-279
Phenotype where environments contain YK-4-279
Phenotype modified by environments containing YK-4-279
Phenotype affecting YK-4-279
Human Disease Model
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