Search Ontology:
ChEBI
L-buthionine-(S,R)-sulfoximine
- Term ID
- CHEBI:94288
- Synonyms
-
- (2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid
- (2S)-2-amino-4-(S-butylsulfonimidoyl)butanoic acid
- (2S)-2-amino-4-(S-butylsulfonimidoyl)butyric acid
- L-BSO
- L-buthionine (SR)-sulfoximine
- L-buthionine sulfoximine
- L-buthionine-(S,R)-sulfoximine
- L-buthionine-(S,R)-sulphoximine
- Definition
- A 2-amino-4-(S-butylsulfonimidoyl)butanoic acid which has S-configuration. It is a inhibitor of gamma-glutamylcysteine synthetase and glutathione (GSH) biosynthesis and is capable of enhancing the apoptotic effects of several chemotherapeutic agents.
- References
-
- CAS:83730-53-4
- Chemspider:106767
- LINCS:LSM-4915
- PMID:12184532
- PMID:15960602
- PMID:18587629
- PMID:19167492
- PMID:21172425
- PMID:24912031
- PMID:25921122
- PMID:26153194
- PMID:30325050
- PMID:31461931
- PMID:31766654
- PMID:32028640
- PMID:32146577
- PMID:32575563
- PMID:32617545
- PMID:32639526
- PMID:32788523
- PMID:32812608
- PMID:33198939
- PMID:33303231
- PMID:9467825
- PMID:9504394
- Reaxys:2367136
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse has_part
-
Show first 5 Terms
Phenotype
Phenotype resulting from L-buthionine-(S,R)-sulfoximine
Phenotype where environments contain L-buthionine-(S,R)-sulfoximine
Phenotype modified by environments containing L-buthionine-(S,R)-sulfoximine
Human Disease / Model Data
Citations