Search Ontology:
ChEBI
PD169316
- Term ID
- CHEBI:93358
- Synonyms
-
- 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole
- 4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
- 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine
- 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]-pyridine
- J1.342.800J
- PD 169316
- PD-169316
- Definition
- A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-nitrophenyl, 4-fluorophenyl, and pyridin-4-yl groups, respectively. It is a potent inhibitor of p38 MAP kinase (IC50 = 89 nM).
- References
-
- CAS:152121-53-4
- DrugBank:DB17040
- HMDB:HMDB0244687
- LINCS:LSM-3731
- PMID:10820206
- PMID:11306695
- PMID:11544639
- PMID:12181122
- PMID:12694807
- PMID:14521923
- PMID:15634764
- PMID:18077363
- PMID:19010935
- PMID:22069054
- PMID:24032631
- PMID:25130739
- PMID:28545002
- PMID:28958943
- PMID:30359932
- PMID:30986374
- PMID:32542535
- PMID:34411914
- PMID:37075613
- PMID:38148557
- PMID:38743735
- PMID:39252535
- PMID:39727341
- PMID:39739720
- PMID:40191451
- PMID:40218465
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from PD169316
Phenotype where environments contain PD169316
Phenotype modified by environments containing PD169316
Phenotype affecting PD169316
Human Disease Model