LY-2183240

Term ID

CHEBI:92670

Synonyms

• 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide
• 5-([biphenyl]-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide
• 5-[([1,1'-biphenyl]-4-yl)methyl]-N,N-dimethyl-1H-tetrazole-1-carboxamide
• LY 2183240
• LY2183240
• N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1-tetrazolecarboxamide

Definition

A member of the class of tetrazoles that is 1H-tetrazole substituted by N,N-dimethylcarbonyl and [biphenyl]-4-ylmethyl groups at positions 1 and 5, respectively. It was developed by Eli Lilly as a potent inhibitor of anandamide re-uptake and fatty acid amide hydrolase, the enzyme responsible for degrading anandamide.

References

• cas:874902-19-9
• lincs.smallmolecule:LSM-2839
• pubmed:16736384
• pubmed:16866524
• pubmed:17452063
• pubmed:18597752
• pubmed:18660824
• pubmed:19022239
• pubmed:20838777
• pubmed:24769262
• pubmed:26126926
• pubmed:28107590
• pubmed:29335158
• pubmed:29504066
• pubmed:36880938
• pubmed:36893812
• wikipedia.en:LY-2183240

Ontology

ChEBI  ( EBI )