Search Ontology:
ChEBI
SL-327
- Term ID
- CHEBI:92211
- Synonyms
-
- 3-amino-3-[(4-aminophenyl)sulfanyl]-2-[2-(trifluoromethyl)phenyl]acrylonitrile
- 3-amino-3-[(4-aminophenyl)thio]-2-[2-(trifluoromethyl)phenyl]-2-propenenitrile
- alpha-{amino[(4-aminophenyl)thio]methylene}-2-(trifluoromethyl)benzeneacetonitrile
- SL 327
- SL327
- Definition
- A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.
- References
-
- CAS:305350-87-2
- LINCS:LSM-2253
- PMID:10969080
- PMID:12490588
- PMID:18766328
- PMID:21074569
- PMID:21312031
- Reaxys:9423720
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from SL-327
Phenotype where environments contain SL-327
Phenotype modified by environments containing SL-327
Human Disease Model