6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

Term ID

CHEBI:92053

Synonyms

6-chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione
6-chloro-7-(2-morpholin-4-ylethylamino)-quinoline-5,8-dione
6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione
6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dione
CDC25 phosphatase inhibitor II
DA-3003-01
DA-3003-1
DA3003-1
NSC 663284
NSC-663284
NSC663284
SPS8I1

Definition

A quinolone that is quinoline-5,8-dione substituted by chloro and [2-(morpholin-4-yl)ethyl]amino groups at positions 6 and 7, respectively. It is a potent and irreversible inhibitor of Cdc25 isoforms.

References

cas:383907-43-5
drugbank:DB17038
lincs.smallmolecule:LSM-2042
pdb-ccd:CQD
pubmed:11708908
pubmed:12356752
pubmed:14718602
pubmed:14988404
pubmed:16155209
pubmed:17970046
pubmed:18245669
pubmed:18699726
pubmed:28994029
pubmed:29186901
pubmed:31541869
pubmed:34426152
pubmed:36642961
pubmed:37302341
pubmed:38255157

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

Phenotype where environments contain 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

Phenotype modified by environments containing 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

Phenotype affecting 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione

Human Disease Model