tianeptine

Term ID

CHEBI:91749

Synonyms

• (+-)-7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide
• (+-)-tianeptine
• 7-{[(11RS)-3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl]amino}heptanoic acid
• rac-7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid
• rac-tianeptine
• racemic tianeptine
• tianeptina
• tianeptine
• tianeptinum

Definition

A racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs).

References

• cas:72797-41-2
• chemspider:62102
• drugcentral:2650
• hmdb:HMDB0042038
• kegg.drug:D02575
• lincs.smallmolecule:LSM-1626
• pubmed:27693216
• pubmed:30550394
• pubmed:30612921
• pubmed:31160227
• pubmed:31425465
• pubmed:31924532
• pubmed:32122858
• pubmed:32134888
• pubmed:32552075
• pubmed:33065230
• pubmed:33154348
• pubmed:33410462
• pubmed:33433378
• pubmed:33608048
• pubmed:33909525
• pubmed:34134575
• pubmed:34195969
• pubmed:34464676
• pubmed:34493757
• pubmed:34593976
• pubmed:34819526
• pubmed:34966012
• pubmed:35211768
• pubmed:3771709
• wikipedia.en:Tianeptine

Ontology

ChEBI  ( EBI )