Search Ontology:
ChEBI

CHIR-265

Term ID
CHEBI:91451
Synonyms
  • 1-methyl-5-({2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
  • CHIR 265
  • CHIR265
  • RAF 265
  • RAF-265
  • RAF265
Definition
A member of the class of benzimidazoles that is 1H-benzimidazole substituted by methyl, [4-(trifluoromethyl)phenyl]amino, and {2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy groups at positions 1, 2, and 5, respectively. It is an inhibitor of RAF kinases, including the BRAF V600E mutant.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from CHIR-265
Phenotype where environments contain CHIR-265
Phenotype modified by environments containing CHIR-265
Human Disease / Model Data
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