Search Ontology:
ChEBI
linifanib
- Term ID
- CHEBI:91435
- Synonyms
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- 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
- ABT 869
- ABT-869
- ABT869
- linifanib
- linifanibum
- N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea
- Definition
- A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 2-fluoro-5-methylphenyl group, while the other is substituted by a p-(3-amino-1H-indazol-4-yl)phenyl group. It is a potent, selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases.
- References
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- CAS:796967-16-3
- KEGG:D09635
- LINCS:LSM-1183
- PMID:16648571
- PMID:16648572
- PMID:17343372
- PMID:19255283
- PMID:19642998
- PMID:20197394
- PMID:21505059
- PMID:22833179
- PMID:23490884
- PMID:24533632
- PMID:26958495
- Reaxys:11008713
- Wikipedia:Linifanib
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from linifanib
Phenotype where environments contain linifanib
Phenotype modified by environments containing linifanib
Human Disease / Model Data