Search Ontology:
ChEBI

adavosertib

Term ID
CHEBI:91414
Synonyms
  • 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one
  • adavosertib
  • adavosertibum
  • AZD 1775
  • AZD-1775
  • AZD1775
  • MK 1775
  • MK-1775
  • MK1775
Definition
A member of the class of pyrazolopyrimidines that is 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one substituted by 6-(2-hydroxypropan-2-yl)pyridin-2-yl, prop-1-en-3-yl, [4-(4-methylpiperazin-1-yl)phenyl]amino groups at positions 1, 2, and 6, respectively. It is a potent and selective oral inhibitor of WEE1 kinase.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from adavosertib
Phenotype where environments contain adavosertib
Phenotype modified by environments containing adavosertib
Human Disease Model
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