Search Ontology:
ChEBI
momelotinib
- Term ID
- CHEBI:91407
- Synonyms
-
- CYT 11387
- CYT 387
- CYT-11387
- CYT-387
- CYT387
- GS-0387
- LM-1149
- momelotinib
- momelotinibum
- N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide
- N-(cyanomethyl)-4-(2-((4-(morpholin-4-yl)phenyl)amino)pyrimidin-4-yl)benzamide
- N-(cyanomethyl)-4-(2-((4-morpholinophenyl)-amino)pyrimidin-4-yl)benzamide
- N-(cyanomethyl)-4-[2-[4-(4-morpholinyl)anilino]-4-pyrimidinyl]benzamide
- N-(cyanomethyl)-4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzamide
- Ojjaara
- Definition
- A benzamide obtained by formal condensation of the carboxy group of 4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzoic acid with the primary amino group of aminoacetonitrile. It is an ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 nM and 18 nM, respectively. Used for the treatment of patients with intermediate- or high-risk myelofibrosis.
- References
-
- CAS:1056634-68-4
- DrugBank:DB11763
- KEGG:D10315
- LINCS:LSM-1141
- PDBeChem:C87
- PMCID:PMC10431522
- PMID:19762238
- PMID:21079613
- PMID:23459451
- PMID:25322686
- PMID:25511866
- PMID:27634203
- PMID:27785927
- PMID:28622623
- PMID:28930494
- PMID:28960447
- PMID:29024542
- PMID:29263442
- PMID:29275119
- PMID:29283448
- PMID:29311136
- PMID:29515114
- PMID:30087028
- PMID:30105668
- PMID:31450973
- PMID:31560729
- PMID:34768286
- PMID:35045875
- PMID:35255234
- PMID:35413417
- PMID:35603634
- PMID:35869266
- PMID:36349465
- PMID:36599841
- PMID:36709073
- PMID:36861402
- PMID:37021939
- PMID:37039727
- PMID:37042865
- PMID:37517413
- PMID:37908862
- PMID:37989928
- PMID:38164985
- Wikipedia:Momelotinib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from momelotinib
Phenotype where environments contain momelotinib
Phenotype modified by environments containing momelotinib
Human Disease / Model Data
Citations