lumacaftor

Term ID

CHEBI:90951

Synonyms

3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid
lumacaftor
VRT 826809
VRT-826809
VX 809
VX-809

Definition

An aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amide benzodioxoles benzoic acids cyclopropanes organofluorine compound ... Show All 6 Terms

aromatic amide benzodioxoles benzoic acids cyclopropanes organofluorine compound pyridines Show first 5 Terms
has_role: CFTR potentiator orphan drug

CFTR potentiator orphan drug Show first 5 Terms
inverse has_part: Orkambi

Orkambi Show first 5 Terms

Phenotype

Phenotype resulting from lumacaftor

Phenotype where environments contain lumacaftor

Phenotype modified by environments containing lumacaftor

Human Disease / Model Data

Citations