Search Ontology:
ChEBI
lumacaftor
- Term ID
- CHEBI:90951
- Synonyms
-
- 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid
- lumacaftor
- VRT 826809
- VRT-826809
- VX 809
- VX-809
- Definition
- An aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis.
- References
-
- CAS:936727-05-8
- Drug_Central:5010
- KEGG:D10134
- PMID:24771136
- PMID:24973281
- PMID:25981758
- PMID:26071414
- PMID:26416827
- PMID:26417173
- PMID:26492939
- PMID:26506855
- PMID:26510034
- PMID:26510035
- PMID:26567541
- PMID:26581802
- PMID:26718821
- Reaxys:12892616
- Wikipedia:Lumacaftor
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from lumacaftor
Phenotype where environments contain lumacaftor
Phenotype modified by environments containing lumacaftor
Human Disease Model