ixazomib

Term ID

CHEBI:90942

Synonyms

ixazomib
MLN 2238
MLN-2238
MLN2238
N-[(1R)-1-borono-3-methylbutyl]-N(2)-(2,5-dichlorobenzoyl)glycinamide

(all 5)

Definition

A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma.

References

(all 27)

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzamides boronic acids dichlorobenzene glycine derivative

benzamides boronic acids dichlorobenzene glycine derivative Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer drug metabolite orphan drug proteasome inhibitor

antineoplastic agent apoptosis inducer drug metabolite orphan drug proteasome inhibitor Show first 5 Terms
inverse has_functional_parent: ixazomib citrate

ixazomib citrate Show first 5 Terms

Phenotype

Phenotype resulting from ixazomib

Phenotype where environments contain ixazomib

Phenotype modified by environments containing ixazomib

Phenotype affecting ixazomib

Human Disease Model