rolapitant hydrochloride hydrate

Term ID

CHEBI:90911

Synonyms

(5S,8S)-8-(((1R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro(4.5)decan-2-one monohydrochloride monohydrate
(5S,8S)-8-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-2-oxo-8-phenyl-1,7-diazaspiro[4.5]decan-7-ium chloride--water (1/1)
(5S,8S)-8-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride--water (1/1)
Rolapitant HCl
Rolapitant hydrochloride
rolapitant monohydrochloride monohydrate
rolapitant.HCl.H2O
Sch 619734
SCH619734
VARUBI

Definition

A hydrate that is the monohydrate form of rolapitant hydrochloride. Used for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

References

CAS:914462-92-3
KEGG:D08988
PMID:26467681
PMID:26535019
Reaxys:15570190

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from rolapitant hydrochloride hydrate

Phenotype where environments contain rolapitant hydrochloride hydrate

Phenotype modified by environments containing rolapitant hydrochloride hydrate

Phenotype affecting rolapitant hydrochloride hydrate

Human Disease Model