Search Ontology:
ChEBI

rolapitant

Term ID
CHEBI:90908
Synonyms
  • (5S,8S)-8-({(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one
  • rolapitant
  • SCH 619734
  • SCH-619734
Definition
An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from rolapitant
Phenotype where environments contain rolapitant
Phenotype modified by environments containing rolapitant
Phenotype affecting rolapitant
Human Disease Model
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