selexipag

Term ID

CHEBI:90844

Synonyms

2-{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}-N-(methanesulfonyl)acetamide
ACT 293987
ACT-293987
NS 304
NS-304
selexipag
Uptravi

Definition

A member of the class of pyrazines that is N-(methanesulfonyl)-2-{4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetamide carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. An orphan drug used for the treatment of pulmonary arterial hypertension. It is a prodrug for ACT-333679 (the free carboxylic acid).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine ether monocarboxylic acid amide N-sulfonylcarboxamide pyrazines ... Show All 6 Terms

aromatic amine ether monocarboxylic acid amide N-sulfonylcarboxamide pyrazines tertiary amino compound Show first 5 Terms
has_functional_parent: ACT-333679

ACT-333679 Show first 5 Terms
has_role: orphan drug platelet aggregation inhibitor prodrug prostacyclin receptor agonist vasodilator agent

orphan drug platelet aggregation inhibitor prodrug prostacyclin receptor agonist vasodilator agent Show first 5 Terms

Phenotype

Phenotype resulting from selexipag

Phenotype where environments contain selexipag

Phenotype modified by environments containing selexipag

Human Disease / Model Data

Citations