Search Ontology:
ChEBI

selexipag

Term ID
CHEBI:90844
Synonyms
  • 2-{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}-N-(methanesulfonyl)acetamide
  • ACT 293987
  • ACT-293987
  • NS 304
  • NS-304
  • selexipag
  • Uptravi
Definition
A member of the class of pyrazines that is N-(methanesulfonyl)-2-{4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetamide carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. An orphan drug used for the treatment of pulmonary arterial hypertension. It is a prodrug for ACT-333679 (the free carboxylic acid).
References
  • cas:475086-01-2
  • drugcentral:5077
  • kegg.drug:D09994
  • pubmed:24392948
  • pubmed:25277144
  • pubmed:25552906
  • pubmed:25850750
  • pubmed:25851691
  • pubmed:26152132
  • pubmed:26291199
  • pubmed:26567613
  • pubmed:26699168
  • reaxys:11140227
  • wikipedia.en:Selexipag
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from selexipag
Phenotype where environments contain selexipag
Phenotype modified by environments containing selexipag
Phenotype affecting selexipag
Human Disease Model