CHZ868

Term ID

CHEBI:90828

Synonyms

CHZ 868
CHZ-868
N-(4-{[2-(2,4-difluoroanilino)-1,4-dimethyl-1H-benzimidazol-5-yl]oxy}pyridin-2-yl)acetamide
N-[4-[2-[[2,4-bis(fluoranyl)phenyl]amino]-1,4-dimethyl-benzimidazol-5-yl]oxypyridin-2-yl]ethanamide

Definition

A memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl)oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetamides aromatic amine aromatic ether benzimidazoles difluorobenzene ... Show All 7 Terms

acetamides aromatic amine aromatic ether benzimidazoles difluorobenzene pyridines secondary amino compound Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

antineoplastic agent EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from CHZ868

Phenotype where environments contain CHZ868

Phenotype modified by environments containing CHZ868

Human Disease / Model Data