Search Ontology:
ChEBI
talmapimod
- Term ID
- CHEBI:90683
- Synonyms
-
- 2-(6-chloro-5-{(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide
- SCIO 469
- SCIO-469
- SCIO469
- Scios 469
- talmapimod
- Definition
- An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.
- References
-
- CAS:309913-83-5
- KEGG:D09386
- PDBeChem:469
- PMID:20201574
- PMID:21659629
- PMID:22868770
- PMID:23032694
- PMID:23841999
- PMID:25749612
- Reaxys:11328447
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from talmapimod
Phenotype where environments contain talmapimod
Phenotype modified by environments containing talmapimod
Human Disease Model