Search Ontology:
ChEBI
torin 2
- Term ID
- CHEBI:90682
- Synonyms
-
- 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one
- torin2
- Definition
- A member of the class of pyridoquinolines that is benzo[h][1,6]naphthyridin-2-one carrying additional 3-(trifluoromethyl)phenyl and 6-aminopyridin-3-yl substituents at positions 1 and 9 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.
- References
-
- lincs.smallmolecule:LSM-1080
- pdb-ccd:17G
- pubmed:23436801
- pubmed:23636326
- pubmed:24459013
- pubmed:24583924
- pubmed:24667246
- pubmed:24801387
- pubmed:25296981
- pubmed:25945839
- pubmed:26023849
- pubmed:26239364
- pubmed:26722032
- reaxys:20268159
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from torin 2
Phenotype where environments contain torin 2
Phenotype modified by environments containing torin 2
Phenotype affecting torin 2
Human Disease Model